Are there any other quests that have been inspirational for pen and paper games? Any quests that you would want to try to replicate as is in dnd?
Shortly after Dryad and the Demigod released, I made a boss who would insult the players at the top of the turn order in a battle of the bands style arena setting, where characters were on hot mic speaking stones after their music battle dissolved into combat. They would have 30 seconds to create the best comeback, then continue to fight using normal DND rules. If it was good or roleplayed well, the crowd would turn to their side, offering a buff to the party for that turn.
I think Mira's Sleepless Nights would make an excellent one shot, personally. Finding Canton Parthilcar's journal before fighting him at the end was a cool moment for me.