Curse Cleansing Cards are always the thing I most want to see.
As far as random loot goes, it would be good if it were less random. Imagine, for example, if every time a sceptre dropped it had the same element for everything. For example, Combusion X, Insightful Combustion Y, Fire Spell Lore Z. Since all 3 stats are fire there is a very real chance that some people would find random loot to occasionally be better than their current fire sceptre. I'm sure many of us use the level 12 caster sceptres from the Planar Eyes chain, and they might still be the best level 12 sceptres in the game, but if random loot dropped like this then it would be entirely possible to find a level 10 or 11 sceptre better than what you had been using until level 12, and a level 13 through 19 sceptre that was better than the level 12 sceptre.
Random loot is really only garbage because they put abilities on it that don't go with the other abilities.