If you want to utilize Cannith Crafting, don't use your main (or any questing toon) for this - because if you die, your crafting progress is gone and you need to start over. Make a special character for it - best one is human, because humans can take Mark of Making feat, which can give you up to +10 to crafting skills.
Same goes for trading - use a mule to post items on AH, because if you die - you can't get your items back until the Afterparty or server transfer.
Collectables are valuable - make sure you empty your bags to your shared Crafting Storage on every bank visit.
Use collectable vendors - they can give you useful potions, like GH.
Get that House P favor as soon as you can. 60-minute Elemental Resist 20 with Jump and Water Breathing is super useful!
Zerg with caution - it can easily cause red alert, which proved many times to be fatal for some characters, even in the wilderness zones...